Researchers at ETH Zurich have used CRISPR methods to develop the first dual-core cell-based biological computer. While biocomputers are relatively slow, the alphabet is much larger and they can use a much larger base system than binary or decimal, at a fraction of the energy cost. While there is still a long way to go before biocomputers can catch up to traditional silicon-based computers, this is exciting progress in this space.

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https://sciencebusiness.net/network-news/eth-researchers-use-crispr-technology-develop-biosynthetic-dual-core-cell-computer